[Nexus Analytics] Newly Launched Uniaxial Powder Tester Unlocks the Potential of Powder Testing

The introduction of an instrument offering a new powder testing technique opens up fresh possibilities for optimising powder handling processes. Tim Freeman, Managing Director, Freeman Technology, considers the merits of uniaxial testing, which include low equipment costs and fast measurement, and explores the benefits it offers to the powder bulk handling industry.

 Traditional approaches to powdercharacterisation within the bulk solids handling industry range from the truly manual – a subjective visual or textural assessment – to tests such as angle of repose and Carr’s Index. In recent years, the need for greater relevance to powder processing has drawn attention to the limitations of these methods, and those at the forefront of bulk powder handling have embraced instruments such as the FT4 Powder Rheometer (Freeman Technology) and 

(biaxial) shear cell analysis. However, the investment costs associated with such systems – in terms of equipment, training and ongoing manpower – are significant and have sometimes been a hurdle.

 The launch of a new uniaxial powder tester offers the bulk powder handling community new choices for powdercharacterisation. Combining low upfront costs, fast measurement times and good repeatability, the Uniaxial Powder Tester (UPT, Freeman Technology) has the potential to extend routine,high valuetesting within the bulk solids handling industry in order to improve the effectiveness of equipment design and operation.

Uniaxial testing: a straightforward technique…

Uniaxial testing has long been recognised for its potential to offer simple, straightforward powder characterisation. In basic terms it measures the stress required to break or fail a consolidated column of powder, thereby directly measuring the unconfined yield strength (UYS) of a powder as a function of a preconsolidation or major principle stress, σ1. The uniaxial UYS (uUYS) is similar to the UYS, a parameter derived by extrapolation in biaxial shear testing, one of the most widely deployed powder characterisation methods. Due to differences in the consolidation and failure protocols applied by the two techniques, the absolute values for uUYS and UYS are not always identical, but the two parameters will rank the flowability of powders in a closely similar way. 

Figure 1: Uniaxial testing involves the construction of a uniformly consolidated powder column and its subsequent fracture through the application of a compressive force. 

 Figure 1 shows the simple procedures that underpin uniaxial measurements. The first step is to produce a stable column by loading the sample into a cylinder and applying a known consolidation stress σv (a).  Detaching the cylinder then leaves a free-standing column (b) that is subsequently fractured through the application of a steadily increasing compressive stress (c). The stress at which the column fractures equals the uUYS of the powder for the given preconsolidation stress.

 By enabling direct measurement, uniaxial testing eliminates errors typically associated with determining UYS via the extrapolation process involved in biaxial testing. Variability of just 10% in the extrapolation process can magnify into changes in UYS values of greater than 100% so this is an important gain. Time savings in data analysis are also substantial.

 … suitable for a wide range of materials.

 Realising the benefits of uniaxial testing has required a major step forward in powder testing technology. In recent decades powder testing instrumentation has become progressively more precise and automated, offering an enhanced platform for the development of uniaxial testing protocols. The launch of the UPT exemplifies this progress, bringing new options for routine powder testing.

 A key challenge with uniaxial testing, especially for more free-flowing materials, is the initial construction of a free-standing consolidated powder column. This issue has been directly addressed in the UPT, partly by implementing double-ended consolidation, which ensures better uniformity of consolidation through the powder column and extends the applicability of the instrument to a broad range of materials.


Figure 2: uUYS data for six different powder samples measured by uniaxial testing shows the range of materials for which it is suitable.

 The UPT has demonstrated its versatility through the measurement of six different powder samples:

  • CRM116 Limestone (Commission of the European Communities, 4mm, angular)
  • Microcrystalline Cellulose (Avicel PH101 – FMC Europe N.V., Belgium, 50mm, irregular)
  • Commercial Talc Powder (20mm, platelets)
  • Methyl Cellulose (Metolose 90H, Shin Etsu, Japan, 83.4µm, fibrous)
  • Lactose 1 (Lactohale LH200, DFE Pharma, Germany, 5-160µm, tomahawk)
  • Lactose 2-(Respitose ML006, DFE Pharma, Germany 2-45µm, tomahawk)

These materials were selected on the basis of their flowability - which ranges from cohesive (e.g. Lactose 2) to the easy-flowing (e.g. Lactose 1 and talc) - and for their industrial relevance. The results show that the uniaxial technique can characterise and differentiate samples that span a wide range of behaviour, confirming its ability to support applications across the bulk powder handling industries.

 Comparing uniaxial testing to other available techniques

Like a number of powder testing techniques, uniaxial testing can clearly be used for a range of materials and it quantifies powders using an established metric. This then raises the question of how the practicalities of measurement compare with the alternatives, and the potential benefits of adoption.

 Generally speaking, when compared with uniaxial testing: 

  • Biaxial shear cell analysis is a slower measurement, has higher equipment cost and a higher training burden. However, biaxial shear cell data remains essential for the application of hopper design methodologies and has the advantage of allowing testing under lower consolidation stresses. This can make the resulting data more relevant to certain process environments.
  • Simple techniques, such as Angle of Repose, Tapped Density and Flow through an Orifice, offer comparable testing times and lower equipment costs. However, uniaxial testing delivers greater repeatability and improved process relevance, making it more effective for QA/QC and process troubleshooting. For example, unlike Flow through an Orifice methods, uniaxial testing is not prone to generating unusual or null results for certain free-flowing or cohesive materials such as colloidal silica.  

 Table 1 summarises the relative merits of these three powder testing techniques which are all routinely used by the bulk powder handling industry, providing guidance for a rigorous appraisal of the alternatives.

Table 1: A summary of the relative benefits and practicalities of uniaxial, shear cell and simple powder testing techniques

 In summary, uniaxial testing meets industrial requirements for quick powder testing by relatively non-expert analysts, with the additional benefit of low equipment costs, and high process relevance.


The commercial introduction of instrumentation for uniaxial testing brings a new technique for the bulk powder handling industries that is straightforward and well suited to routine application within the industrial environment. Measurement times are typically in the order of a few minutes per sample, and training requirements and equipment costs are low. The generated parameter, uUYS, is similar to that measured indirectly via biaxial shear cell analysis and measurements are highly repeatable. These advantages make uniaxial testing highly worthy of consideration when assessing the options for introducing powder testing in an industrial setting and enhancing existing techniques in order to drive up the efficiency of bulk powder handling processes.


  • Industrial Analysis business of renowned scientific instrumentation company acquired by Hitachi High Technologies Corporation for a consideration of £80m.
  • A new company has been created and intends to expand its industrial analytical solutions offer.

Oxford, UK, 3rd July 2017: Oxford Instruments’ Industrial Analysis division today became part of Hitachi High-Technologies Group.

A new company, Hitachi High-Tech Analytical Science, brings together Hitachi High-Technologies’ extensive scientific instrumentation portfolio with Oxford Instruments’ rich 40-year heritage of innovative analytical instruments and services developed in close partnership with industry customers. The collaboration will offer the companies a wider ranging product portfolio, more contact points with customers and more chances to meet customer needs.

Hitachi High-Tech Analytical Science will continue to specialise in delivering high-tech analysis solutions, developed in close collaboration with industry customers and designed to meet the tough challenges of a rapidly evolving industrial sector.  The company’s range of laboratory-based and robust high-performance in-field testing instruments deliver materials and coatings analysis that adds value throughout the production lifecycle, from raw material exploration to incoming inspection, production and quality control to recycling. A team of in-house experts have developed customised testing methodologies for hundreds of industrial applications, delivering simplicity of operation for even the most demanding applications.

Dawn Brooks, Managing Director of Hitachi High-Tech Analytical Science said: “Today, we already help thousands of businesses streamline their costs, minimise risk and increase production efficiency. The combined strengths of Hitachi and Oxford Instruments Industrial Analysis greatly increases our capability to offer an ever wider range of leading-edge analytical solutions to our customers around the world”.

Neoscience | A Beginning-To-End Genomics Solution Provider, for Research and In Vitro Diagnostics

Neoscience, formerly as the Department of Life Science in Science Valley, is now one of the leading distributors of laboratory supplies, molecular biology products, genomics solutions, benchtop research instruments and molecular diagnostics products in Malaysia. Along years, Neoscience has been appointed as the sole distributor of Axygen, TPP, Seegene, Agilent Technologies (genomics solutions) and Thermo Scientific in Malaysia.

With our brands, we offer a comprehensive range of molecular biology products, genomics solutions, in vitro diagnostics products, services and expertise. We provide excellent quality products with timely delivery and services to our customers at a competitive price, hoping to give them the greatest confidence in our solutions.

Please visit our webpage at www.neoscience.com.my  for more information. Should you need further assistance or samples, please call us at +603 7610 0388.

Agilent’s Ultivo Triple Quadrupole LC/MS

The Ultivo triple quad is a transformative approach to LC/MS that integrates several hardware and software innovations designed to deliver even more improved business results for customers.

Ultivo is optimized to address the food and environmental routine testing segments employing triple quad LC/MS systems for quantitative analyses. Ultivo delivers robust performance, superior uptime, and easier serviceability, in a footprint that is 70% smaller than previous instruments. Customers can now significantly increase their analytical throughput without having to increase the size of their existing laboratories.

"We are a production lab experiencing some significant growth, so the ability to place more instrumentation in the same footprint in the lab is important," said Johnny Mitchell, president at ESC Lab Sciences in Nashville, TN. "Without that ability we would be faced with some expensive construction costs to increase the size of our facilities."

In addition to its trendsetting size, Ultivo provides reproducible, reliable assays that result in exceptional performance in complex matrices. Greater ion transmission efficiency leads to optimized sensitivity; and improved, intelligent diagnostics use intuitive readbacks that can quickly identify issues, ensuring optimum uptime. Furthermore, Ultivo's new VacShield vacuum provides vent-less ion injector exchange capabilities that reduce wear and tear and facilitate rapid front-end maintenance.

"Agilent prides itself on actively listening to customers, and addressing their needs through the continuous development of innovative technology solutions. Ultivo provides a revolutionary new 'fit for purpose' triple quad LC/MS, that is smaller than could've been imagined, yet delivers the superior performance usually associated with much larger instruments," said Monty Benefiel, vice president and general manager of Agilent's Mass Spectrometry Division. "We are excited by our customers' reactions so far, and expect that Ultivo will dramatically change the LC/MS landscape now, and for years to come."

If you would like more information on the new Ultivo Triple Quadrupole LC/MS visit the product information page here (http://www.agilent.com/en/products/mass-spectrometry/lc-ms-instruments/triple-quadrupole-lc-ms/ultivo-triple-quadrupole-lc-ms). Speak to our sales personnel at Booth 4AD01, this 10 – 12 October at Putra World Trade Centre, Kuala Lumpur.

Thermo Fisher Scientific presents the Apreo SEM – The most versatile high-performance SEM

The image shows a scanning electron micrograph of GaAs nanowires on a silicon substrate. These self-catalyzed GaAs wires were grown from the gallium droplets that can be seen on the wire tips.

For this sample and many others, SEM is a proven technique for resolving the topography of the nanomaterials while displaying excellent contrast between the various constituents. However, acquiring such materials contrast can be daunting when those materials are insulators, exhibit sensitivity to electron beams, or are similar in composition. In these cases, it is a challenge to achieve this contrast quickly, at TV-rate scanning, with low noise and at short working distance, or from a tilted perspective.

To solve all these challenges associated with materials contrast imaging, FEI recently launched the all-new Apreo SEM, featuring a unique in-lens backscatter detector (T1). Apreo’s T1 detector captures backscatter signal as soon as the beam is switched on. Because it is positioned at the bottom of the column, intense materials contrast is available all the way from navigation to imaging the smallest details. With sensitivity to beam currents as low as only a few pA, it is ideal for imaging sensitive samples that would otherwise be damaged.

Apreo further improves materials contrast with a novel compound electrostatic-magnetic final lens. Compound lens filtering was used in this image to enhance the contrast between two materials that are very close in average atomic weight (Ga and GaAs). Moreover, the compound lens filter can be used to filter out charging signal, enabling charge-free imaging on insulators in cases where excellent low-beam energy and low-current performance are not enough.

Combined with a range of features that make the microscope versatile, effective, and easy to use, Apreo’s excellent detection gives researchers the contrast they need to advance scientific discovery.


Sample courtesy of David Fuster, Andrés Raya, Álvaro San Paulo and María Ujue González in the group “MBE: quantum nanostructure for optoelectronics” at “IMM-Instituto de Microelectrónica de Madrid (CNM-CSIC)”.

Bruker Launches the S8 TIGER Series 2 WDXRF System for Elemental Analysis in Industrial and Academic Research and Materials Quality Control

Bruker announces the launch of its new S8 TIGER™ Series 2, the next-generation Wavelength Dispersive X-Ray Fluorescence (WDXRF) spectrometer. The S8 TIGER Series 2 is the most versatile WDXRF tool available for advanced quantitative elemental analysis in industrial and academic materials research, as well as in industrial quality control (QC) of materials.

The new S8 TIGER Series 2 introduces novel HighSense™ technology which offers an exceptional linear dynamic range, thus enabling higher precision levels for process and quality control in cement, minerals, mining, metals, glass and ceramics applications. In addition, measurement times are significantly reduced, sample throughput is increased, and time-to-result is improved, typically by 25%.

The S8 TIGER Series 2 also features XRF2 small spot mapping for detailed maps of elemental distributions in materials. With a 300µm spot size, XRF2 offers the highest spatial resolution available in WDXRF. This makes the S8 TIGER Series 2 an excellent system for both industrial QC labs as well as for industrial and academic research and methods development laboratories.

In addition, the S8 TIGER Series 2 new HighSense X-ray optics improves both sensitivity and spectral resolution. This benefits a wide range of applications including recognition of foreign particles, optimization of mineral beneficiation processes in mining, analysis of material properties in metals, semiconductors, and nanotechnology.

The S8 TIGER Series 2 offers intuitive and robust operation with a new multilingual TouchControl™ interface. The S8 TIGER Series 2 is designed for high sample throughput and easy integration into automated analytical laboratories. Optimal instrument uptime and low cost of operation are ensured with the unique SampleCare™ feature that protects system components while running liquid petrochemical samples, or powders.

Dr. Kai Behrens, the Bruker AXS Head of XRF Product Management, commented: “The S8 TIGER Series 2 combines unequalled robustness and reliability with highest analytical performance, flexibility and application range in WDXRF. Its new HighSense technology allows tighter quality and process control, while the new XRF2 mapping tool benefits both R&D of new materials, as well as the optimization of industrial processes.”

For more information about the S8 TIGER Series 2, do visit us at booth 4FA01 this coming 10 – 12 October 2017 at Putra World Trade Center, Kuala Lumpur!

DeNovix Honored With Prestigious Reviewers’ Choice Award for Life Science Product of the Year 2017

WILMINGTON, DE – April 7, 2017 – The DeNovix DS11 FX+ spectrophotometer / fluorometer has been awarded the coveted Reviewers’ Choice Award for Best Life Science Product of the Year 2017 at a special ceremony held during the meeting of the American Association of Cancer Research in Washington D.C., USA.

Hosted by SelectScience®, the Scientists Choice Awards® recognize life science products that have made the greatest contribution to enabling scientists in their work. The Reviewers’ Choice Award for Life Science Product of the Year 2017 is given in recognition of the product most highly rated by scientists around the world based on criteria such as ease of use, after sales support and value for money. The DS-11 FX+ is a unique combination of sample microvolume spectrophotometer, cuvette absorbance and fluorometer that enables researchers to gain quick and accurate quantification of nucleic acids and proteins, robust sample quality control and perform a range of UV-Vis and fluorescence applications.

DeNovix Inc. Business Director Kevin Kelley said ”It is a real honor to receive this award that reflects the experience of thousands of scientists around the world who use our products. The number of five star ratings we receive across all the review categories is testament to the dedication and experience of all members of the team we have here at DeNovix and their drive to support our customers.”

DeNovix CEO Fred Kielhorn added, ”Our mission at DeNovix has always been to provide scientists with innovative products that accelerate their work while providing a user experience and level of support that exceeds their expectations. This award demonstrates that we have achieved this with the DS-11 Series. We look forward to sharing future innovations with the scientific community for years to come.”

The DS-11 FX+ is a stand-alone instrument engineered for rapid and accurate UV-Vis and fluorometric analysis across a wide range of applications and industries. The system includes DeNovix’ custom Android™ operating software, Wi-Fi / Ethernet network connectivity and a glove-compatible HD touch screen. Each new instrument is calibrated for life, maintenance free and backed by an industry-leading three-year factory warranty.

The primary applications for the instrument are UV-Vis measurements for nucleic acid and protein quantification, kinetic studies and microbial cell quantification. The intuitive interface helps users quickly create custom methods that may be defined and saved in password-protected accounts. Results are automatically stored and easily exported to e-mail, USB, network folders, network printers, LIMS, USB drives and label printers. IQ/OQ documentation and performance verification software is available to help achieve compliance in GLP/GMP environments.

Source: BioLifeHaus Sdn Bhd

Introducing Bruker, a world’s leading manufacturer of FTIR, NIR and Raman spectrometers.

Bruker Optics

Bruker Optics, part of the Bruker Corporation (NASDAQ:BRKR) is one of the world’s leading manufacturer and worldwide supplier of Fourier Transform Infrared, Near Infrared and Raman spectrometers.

Bruker entered the field of FTIR spectroscopy in 1974. The early instruments set new standards in research FTIR with evacuable optics, high resolution and automatic range change. Since then, the product line has been continuously expanding with instruments suitable for both analytical and research applications with exceptional performance characteristics.

Today, Bruker Optics offers complete technical solutions for various markets which cover a broad range of applications in all fields of research and development as well as industrial production processes for the purpose of ensuring quality and process reliability.

Bruker Optics has a R&D and manufacturing center in Ettlingen, Germany, technical support centers and sales offices throughout Europe, North and South America, Asia, India, Middle East and Africa.


Chemopharm Expands Its Range of Solutions for Laboratory Testing and Research

Chemopharm began in year 1976 and in 2016, we celebrated our 40th anniversary. One key factor through all these 40 years is our commitment to deliver state-of-the -art, high quality products together with top customer satisfaction.

To this end, Chemopharm is focused on delivering great customer experiences and building trust between us and our customers. We strive to continually bring in new technologies and products, in understanding our customers’ needs and requirements, in constantly improving our customer interactions and in ensuring we provide top technical and application support.

This year, among the new brands we are introducing are Seward, Inlabtec AG, LabTex, Charles Ischi AG and Analytik Jena in Malaysiato continue to expand on the range of solutions we are able to provide.

Brief introduction of our New Brands:

Seward: Seward Limited has been manufacturing and developing the legendary Stomacher® Lab Blender for 40 years. The original and still regarded as the best, more than 8 million food samples a day are prepared on Stomacher® 400 paddle blender units around the world.

Labtex: Labtex Laboratory Scale Spray Dryer is a compact, extremely quiet, efficient and simple to operate laboratory spray dryer and yet the most economical methods of evaporation to reduce the liquid feed to solid powder particles complimented by the inclusion of CALgrafix process monitoring software.

Charles Ischi AG: Charles Ischi AG is an established supplier of professional solutions for pharmaceutical quality and in-process control of capsules and tablet testing. Offering semi and fully automatic testing devices to measure parameters such as hardness, thickness, weight, diameter, disintegration, friability, abrasion and API content uniformity.

Inlabtec AG: With the Inlabtec Serial Diluter it is now possible to mix and dilute a sample in a single step which integrates dispensing and mixing. Major benefits are viable cell counts of highest accuracy combined with a comfortable, intrinsically safe workflow.

Analytik Jena: With more than 150 years of experience, starting from the invention of Ernst Abbe and Carl Zeiss, Analytik Jena has grown to be one of the most innovative manufacturers of high-performance precision analytical systems. Analytik Jena has excellent competencies in the fields of Optical Spectroscopy, Sum Parameters and Elemental Analysis.  Being proud of Analytik Jena core competency, a long-term warranty of 10 years was given for their high-performance optics.

We are the authorized distributor for the below leading brands for analytical, life science and health care instruments and consumables.

For more information, please visit our website: www.Chemopharm.com.my, or visit our booth 4AE02 at LabAsia 2017 on 10 – 12 October 2017 at Putra World Trade Centre Kuala Lumpur, Malaysia.

Introducing dynamic flow testing as part of a multi-variate approach to powder characterisation

Dynamic powder testing is a modern technique that directly measures the flow properties of consolidated, conditioned, aerated and even fluidised powders. Dynamic test methods complement shear and bulk property measurements to deliver a comprehensive level of powder characterisation. Used in combination, these three methodologies provide a powerful tool for evaluating the complex behaviour of powders.

What is a powder?

Referring to powders as a single phase can be somewhat simplistic. Powders are typically three-phase systems containing complex and variable solid particles as well as an unquantified amount of air and a degree of moisture. As a result, powder behaviour is an intricate interaction of all three phases and is influenced by a vast array of parameters. This makes both measurement and processing demanding.

Focusing on flow

The way in which a powder flows is one of the most important aspects of its behaviour. Ensuring that powders flow through a plant in a reliable, controlled way is a significant challenge. However, the properties that dictate flow also influence many other unit operations, such as blending and die filling. When a powder moves, the particles within it need to move with respect to each other. The ease with which this occurs determines how readily the powder will flow. This simple statement immediately helps identify factors that influence powder flow. These include the level of friction between particles, which is a function of shape and surface texture, and the likelihood of mechanical interlocking, where particles fit together like jigsaw pieces and exert significant resistance to movement. The degree of cohesion and adhesion is also highly influential. Van der Waals forces, electrostatics and magnetism, amongst others, will all influence the strength with which particles attach to one another. Adhesive forces will also arise from the interaction between particles and container walls as well as from liquid bridging between particles. With denser particles the influence of gravity tends to dominate, but for smaller, lighter particles the cohesive and adhesive forces are relatively large and can therefore define behaviour. These multiple mechanisms make it difficult to predict how a process changes may impact performance. For example, moisture may encourage agglomeration via liquid bridging, it may lubricate the relative movement of rough particles, or even earth an electrostatically charged system, resulting in a different outcome in each case.

Making measurements

The pragmatic response to this complexity has been to develop measurement techniques that classify flow behaviour with just a single figure, such as flow through an orifice, angle of repose or tapped density. These traditional techniques provide some measure of flow but are limited for the purposes of process and product optimisation as they typically suffer from poor repeatability and don’t necessarily generate data that correlate with process performance. Powder processors increasingly recognise the importance of employing a number of complementary techniques to rationalise flow behaviour and the need to adopt methods that generate accurate, reliable and relevant data.

Introducing dynamic testing

Dynamic powder testing involves measuring a powder in motion. A flow energy is determined by measuring the axial and rotational forces acting on a blade as it travels along a defined path through a powder sample. Rotating the blade downwards applies a compacting force by pushing the powder against the base of the test vessel while an upward traverse produces a low stress, lifting action. The resulting parameters are Basic Flowability Energy (BFE) and Specific Energy (SE) respectively which directly quantify how a powder flows under different conditions and have been shown to reliably correlate with process performance. Dynamic powder testing has the benefit of evaluating a flowing powder and, due to the fact that powders can be tested in a consolidated, conditioned, aerated or even fluidised state, the test conditions can be chosen to simulate the process environment. This approach provides a highly sensitive method which is capable of differentiating powders that are otherwise classified as identical.

Assembling a modern powder testing toolkit

Dynamic powder testing represents a significant advance in the field of powder characterisation and one with proven value for powder processors. However, it is most usefully applied in combination with complementary techniques.  Modern powder testers incorporate dynamic, shear and bulk property methodologies in one device. Shear testing is a well-established technique for characterising powders previously consolidated under moderate to high stress conditions. Modern shear cell testers simplify the generation of data required to support the design protocols developed by Jenike. For this reason, they are an important part of the powder testing toolkit although the technique can be employed well beyond its original remit. Figures 1a and 1b show shear and dynamic test data for two samples of titanium dioxide. Shear data indicate that the two samples are identical but the flow energy identifies clear differences suggesting that under certain process conditions, these samples may behave identically but their performance under other conditions may vary significantly.  For example, a hopper designed to handle each material may require the same outlet dimensions but the process parameters for a die filling rig or blender may need to be adjusted because of the distinct differences in dynamic flow properties. This highlights the need for a range of measurements when trying to understand and rationalise powder behaviour.

Bulk parameters such as density, compressibility and permeability are also highly relevant. They are required for certain design calculations but can also be extremely helpful in rationalising complex behaviour patterns. The permeability of a powder, for example, describes how easily a powder transmits or retains air and this has a significant impact on how it behaves in processes such as filling and pneumatic conveying. Information on compressibility is valuable in any environment where a powder is exposed to an external stress such as during storage or in a tablet press. Together, dynamic, shear and bulk properties describe the mechanisms that dictate flow behaviour and provide the information needed for successful process optimisation. This is exemplified by a study in which the dynamic, shear and bulk properties of a limestone sample were measured as a function of moisture content in order to assess the impact of humidity. The shear data remained relatively consistent as moisture content increases but BFE, Compressibility and Permeability exhibited significant changes, (see Figures 2a, b & c.) The increase in the flow energy of limestone suggests that it becomes more cohesive as moisture content increases. This could be due to water acting as a binder, forming liquid bonds that encourage the particles to attach to each other. Compressibility also increased reinforcing the theory that the limestone becomes more cohesive with increasing moisture content. Cohesive powders tend to form agglomerates and air becomes entrained within and between the agglomerates resulting in a more compressible material. Permeability however shows a more unusual response, first decreasing with the introduction of moisture and returning near to its original value as moisture content increases further. This means that in certain processes, performance may degrade as humidity increases but actually improve at higher humidity levels. The response illustrates how changes in process conditions may not affect performance in a predictable manner and demonstrates how multiple parameters are required to comprehensively describe a powder’s response.


There are many powder testing techniques available but in order to deliver value, methods must prove to be reliable, reproducible and relevant. Techniques that meet these essential criteria can guide formulation scientists and process engineers through the challenges of working with powders.

Figures & Images

Figure 1(a)

Figure 1(b)

Figure 2(a)

Figure 2(b)

Figure 2(c)

For more information, please visit our website: www.nexus-analytics.com.my or visit our booth 4AC09 at LabAsia 2017, 10 – 12 October 2017 at Kuala Lumpur, Malaysia.


Nexus Analytics is now the Exclusive Distributor for Netzsch products in Malaysia & Singapore. NETZSCH is well known as the leader of Thermal Analysis Instruments. It has consistently invested over the long term into innovative new developments and advanced technologies, conceived for state-of-the-art application tasks in materials research and development, quality assurance and process optimization.

We have a full suite of demo instruments in both Malaysia & Singapore including DSC, TGA & STA.

About Us

As a leader in the distribution and support of scientific research products in South East Asia, Nexus Analytics represents renowned manufacturers from around the world in providing current and next-generation tools and technologies focusing on integrated solutions and applications, including comprehensive service support to meet your growing needs; from consultation, development and implementation of customized solutions to integrating, installing, commissioning and providing world class technical support.

We exclusively represent and support leading brands of analytical instruments and consumables including:

  • FT-IR, FT Raman, Dispersive Raman and NIR spectrometers (Thermo Scientific)
  • Thermal & Thermophysical Analysis (Netzsch)
  • HPTLC and Flash Chromatography systems and supplies (CAMAG & Biotage)
  • Mercury & Arsenic analyses (PSA)
  • Automated and manual Sample Preparation systems (Biotage)
  • Particle & Powder characterization (Horiba, FreemanTech, Fluidimaging)

Whether you need equipment for sample preparation & purification , material characterization, analytical chemistry or even custom projects, we can meet your expectations and provide a solution.

For more information, please visit our website: www.nexus-analytics.com.my, or visit our booth 4AC09 at LabAsia 2017, 10 – 12 October 2017 at Kuala Lumpur, Malaysia.

Waters Strengthens Malaysia Presence with New Solution Centre

KUALA LUMPUR, February 28, 2017 -- Waters Corporation (NYSE:WAT) announced today the opening of a new Solution Centre in Malaysia designed to advance liquid chromatography and mass spectrometry analytical capabilities. Equipped with application development, demonstration and training facilities, the new Solution Centre in Malaysia further strengthens Waters' footprint in the region while addressing the specific needs of laboratory scientists in Malaysia.

The new Centre will offer customers the innovative and high-tech analytical systems to support the pharmaceutical and life sciences, food and environmental, chemical material and clinical research areas.

"This is another milestone for us to better support customers for their LC/MS applications and their education needs after our office opening in Malaysia. With the increasing demand of customers in the country, the solution centre has deployed advanced technology including the new triple quadrupole mass spectrometer for demonstration and training to the benefits of our valued customers," says Mathieu Laouenan, General Manager - SEA & Australasia, Waters Pacific Pte Ltd.

Located in D7-1-G Block D7, Pusat Perdagangan Dana 1, Jalan PJU 1A/46, 47301 Petaling Jaya, Selangor, the new Centre is equipped with state-of-the-art separation science and mass spectrometry technologies. Currently, the centre houses the ACQUITY® Ultra Performance Convergence Chromatography (UPC2®) system, the award-winning mass detector ACQUITY® QDa®, the XEVO® TQ-S micro triple quadrupole mass spectrometer, the Alliance® HPLC system, and the ACQUITY ArcTM UHPLC system along with related software and sample preparations devices.

“Delivering benefit is Waters’ core value. The investment in this new Solution Centre reinforces that commitment to our customers. Scientists can now choose the right technology platform for their laboratories through firsthand experiences with Waters' technologies, as well as continued training and support after a purchase is made,” says Krishna Kodoth, General Manager - Malaysia, Waters Analytical Instruments Sdn. Bhd.

About Waters Corporation (www.waters.com) Waters Corporation (NYSE:WAT) develops and manufactures advanced analytical and material science technologies for laboratory dependent organizations. For more than 50 years, the company has pioneered a connected portfolio of separations science, laboratory information management, mass spectrometry and thermal analysis systems.


Stephy Lok, +603-7841 1675
Marketing Communications
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